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Manchester City youngsters Sam Edozie and Juan Larios are down on the south coast as they look to complete moves to Southampton before the end of the day.
The deal for Edozie, who appeared certain to break into Pep Guardiola's squad before injury last season, is worth up to £10million.
Saints are understood to have agreed a flat £6m fee for Larios, with the Spanish left back having never played a game for City.
Southampton, who appointed City's former head of youth recruitment Joe Shields as their new head of senior recruitment this summer, have already signed two promising prospects from the Etihad club in this window.
Goalkeeper Gavin Bazunu and midfielder Romeo Lavia have quickly established themselves as starters in Ralph Hasenhuttl's team.
They are now set to be joined by England Under 19 wideman Edozie and versatile Spain Under 19 defender Larios who can operate in both full-back positions.
Southampton are also chasing the signings of Duje Caleta-Carr and Ainsley Maitland-Niles as Ralph Hasenhuttl looks set for a frantic end to the transfer window.